Professor Raphael Mechoulam is an Israeli organic chemist and professor of Medicinal Chemistry at the Hebrew University of Jerusalem in Israel.
Professor Mechoulam was born in Bulgaria (1930), where he studied chemical engineering. After immigrating to Israel he received his MSc in biochemistry from the Hebrew University of Jerusalem and his PhD. at the Weizmann Institute and completed his postdoctoral studies at the Rockefeller Institute in New York. In 1960 he joined the junior staff of the Weizmann Institute, and in 1985 he became a professor at the Hebrew University.
Cannabidiol (CBD) discovered in 1930 by Roger Adams is one of 113 identified cannabinoids in cannabis plants, along with tetrahyrdocannabinol (THC). CBD has been used to treat inflammation and auto-immune conditions
Mechoulam was possibly the most significant academic to shed light on the active principles of the cannabis plant back in the 1960s, when his work at the Weizmann Institute led to the discovery of the human endo-cannabinoid system, giving him the title the “Godfather of cannabis research”. In a recent Global Health Talk with Michael Lesner, Professor Mechoulam reflects on his lifelong work in cannabis research.
In 2020, Professor Raphael Mechoulam was awarded the Harvey Prize for his ground-breaking research in the world of medicinal cannabis. His studies in this field have given the world a new perspective on cannabis as a healing plant, rather than just a recreational drug. Over the years, the Harvey Prize has become a reliable predictor of the famous Noble Prize. Since 1986, more than 30% of Harvey laureates were ultimately awarded the Nobel Prize.
In this Global Health Talks episode, Professor Mechoulam talks about CBD being used to treat multiple disease states in high doses, although not accepted by many as a recognised drug. The drug however has been included in clinical trials for use on epilepsy participants, a journey of 35 years
Through his research work, Professor Mechoulam Cannabis has found other compounds that show potential for clinical treatment, including anxiety. Medical cannabis in Israel has been available with varying levels of CBD and THC, though in there has been limited dispensing of medical cannabis in countries such as the UK. Compounds in the human body that ‘simulate’ effects of THC and CBD require more detailed investigation. Mechoulam argues, cannabis may not be used to target one particular disease state alone, but more generally.
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Preventing surgery related infections
Surgical site infections (SSI) is infection that occurs after surgery in a part of the body where the surgery took place. Surgical site infections are seen as the most common healthcare-associated infection, significantly impacting healthcare resources in the UK and across the World.
Professor Leaper speaks on needing ongoing good antibiotic stewardship to reduce the risk of antibiotic-resistant and emergent organisms. The pressures on administering antibiotics have led to tighter management and stewardship of antibiotics.
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Transformative AI in a COVID World
urrently working back in the clinic as a pediatric cardiologist after a year in telehealth, Dr Anthony Chang is investigating the short and medium impacts of COVID-19. Another area of focus is using AI, “Swarm Learning” and other technologies to share pediatric cardiology information, such as electronic records or images across health systems in the US and across other countries.
The International Council of Nurses represents the 27 millions nurses across 130 national nursing associations right around the world. -
Equitable learning opportunities for new nurses
With over 130,000 students at Western Governors University (WGU) delivering online courses from the US, Dr Jan Jones-Schenk is the Senior Vice President and Executive Dean of the College of Health Professions. The College that Dr Jones-Schenk is Dean of, has approximately 30,000 students following healthcare curricula.
In January 2022, the University marks 25 years as a non-profit academic institution, focused on competency based education delivered through expanded access to rural areas and in an equitable manner to others in the United States. The focus for WGU has been in delivering education regardless of time or place especially in rural communities to locals.
